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84-B10
$120 – $900
Products Details
Product Description
– 84-B10 is a 3-phenylglutaric acid derivative. 84-B10 inhibits cisplatin (HY-17394) induced tubular ferroptosis. 84-B10 attenuates cisplatin-induced mitochondrial damage and oxidative stress. 84-B10 ameliorates cisplatin-induced acute kidney injury (AKI)[1].
Web ID
– HY-44307
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C25H22F3NO5
References
– [1]Fan J, et, al. A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis. Free Radic Biol Med. 2023 Jan;194:84-98.
CAS Number
– 698346-43-9
Molecular Weight
– 473.44
Compound Purity
– 99.62
SMILES
– O=C(O)CC(CC(NC1=CC(C(F)(F)F)=CC=C1OC2=CC=C(OC)C=C2)=O)C3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Ferroptosis
Pathway
– Apoptosis
Product type
– Reference compound
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