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Products Details
Product Description
– 6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic agents and applications in antibody-agent conjugation. 6-O-2-Propyn-1-yl-D-galactose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-128930
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C9H14O6
References
– [1]Ekholm FS, et al. Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody-Drug Conjugation Chemistry. ChemMedChem. 2016 Nov 21;11(22):2501-2505.
CAS Number
– 881895-59-6
Molecular Weight
– 218.20
SMILES
– O=C[C@@H]([C@H]([C@H]([C@@H](COCC#C)O)O)O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Non-cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
