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Products Details
Product Description
– 5-HT6/7 antagonist 1 is a multifunctional ligand that antagonizes 5-HT6/7/2A and D2 receptors, without interacting with M1 receptors and hERG channels.
Web ID
– HY-101622
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H20FN3O3
References
– [1]KoÅ‚aczkowski M, et al. Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia. J Med Chem. 2014 Jun 12;57(11):4543-57.
CAS Number
– 131999-28-5
Molecular Weight
– 393.41
SMILES
– O=C1N(CCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C(C5=C1C=CC=C5)=O
Clinical Information
– No Development Reported
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Dopamine Receptor
Isoform
– 5-HT2 Receptor;5-HT6 Receptor;5-HT7 Receptor;D2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
