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Product Description
– 4-Epianhydrotetracycline hydrochloride is a major intermediate product of Tetracycline (HY-A0107). 4-Epianhydrotetracycline hydrochloride shows lethal effects and induces cell apoptosis of zebrafish embryos. 4-Epianhydrotetracycline hydrochloride inhibits Shewanella, E. coli and P. aeruginosa with MIC values of 2, 1 and 64 mg/L, respectively[1].
Web ID
– HY-136439
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H23ClN2O7
References
– [1]Wang M, et al. Effects of 4-epianhydrotetracycline on oxidative stress in zebrafish (Danio rerio) embryos. Sci Total Environ. 2021 Nov 20;796:149047.|[2]Wang M, et al. Developmental toxicity and transcriptome analysis of 4-epianhydrotetracycline to zebrafish (Danio rerio) embryos. Sci Total Environ. 2020 Sep 10;734:139227. |[3]Long S, et al. Toxicity of tetracycline and its transformation products to a phosphorus removing Shewanella strain. Chemosphere. 2020 May;246:125681.
CAS Number
– 4465-65-0
Molecular Weight
– 462.88
SMILES
– O[C@@](C(C1=C(C2=C3O)O)=O)(C(C(C(N)=O)=C4O)=O)[C@](CC1=C(C2=CC=C3)C)([H])[C@H]4N(C)C.Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis;Bacterial
Isoform
– Tetracycline
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
