4-CMTB
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4-CMTB

SKU T8642-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 853 CAD

Products Details

Product Description

– 4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38).

Web ID

– T8642

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H15ClN2OS

Citations

– 1. Tian P, Yang W, Guo X, et al.Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis.Nature Communications.2023, 14(1): 1-16. 2. Pfanzagl B, Jensen-Jarolim E.Contrary effects of the gut metabolites deoxycholate and butyrate on the acetylcholine-evoked calcium response in an enteroendocrine cell model.Endocrine and Metabolic Science.2024: 100167.

References

– Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J Pharmacol. 2009;158(1):146-153.

CAS Number

– 300851-67-6

Molecular Weight

– C14H15ClN2OS

Compound Purity

– 0.9957

SMILES

– CC(C)C(C(=O)Nc1nccs1)c1ccc(Cl)cc1

Pathway

– GPCR/G Protein|||Endocrinology/Hormones

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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