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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline
Price range: 82 CAD through 291 CAD
Products Details
Product Description
– 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.1,2,3,4,5It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.1,2,3It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib , with antiproliferative activity.4,5
Web ID
– T36102
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H17ClN2O4
References
– Pandey, A., Volkots, D.L., Seroogy, J.M., et al.Identification of orally active, potent, and selective 4-piperazinylquinazolines as antagonists of the platelet-derived growth factor receptor tyrosine kinase familyJ. Med. Chem.45(17)3772-3793(2002)
CAS Number
– 183322-18-1
Molecular Weight
– C14H17ClN2O4
SMILES
– COCCOC1=CC2=NC=NC(Cl)=C2C=C1OCCOC
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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