3-AP
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3-AP

SKU T1982-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 1,531 CAD

Products Details

Product Description

– 3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).

Web ID

– T1982

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C7H9N5S

Citations

– 1. Wang R, Xie S, Zhu S, et al. Targeting matrix metallopeptidase 2 by hydroxyurea selectively kills acute myeloid mixed-lineage leukemia. Cell Death Discovery. 2022, 8(1): 1-10

References

– Martin LK, et al. A dose escalation and pharmacodynamic study of Triapine and radiation in patients with locally advanced pancreas cancer. Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e475-81.

CAS Number

– 143621-35-6

Molecular Weight

– C7H9N5S

Compound Purity

– 0.9733

SMILES

– NC(=S)NN=Cc1ncccc1N

Target

– MMP|||TNF|||Interleukin

Pathway

– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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