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2′,3′-cGAMP sodium
Price range: 395 CAD through 2,448 CAD
Products Details
Product Description
– 2′,3′-cGAMP sodium (2′-3′-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
Web ID
– T10065L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H22N10Na2O13P2
References
– Guo X, et al. Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation. Sci Rep. 2017 Jul 25;7(1):6355.
CAS Number
– 2734858-36-5
Molecular Weight
– C20H22N10Na2O13P2
Compound Purity
– 0.998
SMILES
– OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O
Target
– Others
Pathway
– Immunology/Inflammation
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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