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20-Carboxy-Leukotriene B4
$408
Only 1000 item(s) left in stock.
Products Details
Product Description
– 20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis)[1].
Web ID
– HY-113483
Shipping
– Room temperature
Molecular Formula
– C20H30O6
References
– [1]Anne-Sophie Archambault, et al. 20-Hydroxy- and 20-carboxy-leukotriene (LT) B4 downregulate LTB4 -mediated responses of human neutrophils and eosinophils. J Leukoc Biol. 2019 Jun;105(6):1131-1142.
CAS Number
– 80434-82-8
Molecular Weight
– 366.45
SMILES
– O=C(O)CCC[C@H](O)/C=CC=CC=C[C@H](O)C/C=CCCCCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
