1-β-D-Glucosylsphingadienine (d18:2 (4E
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1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))

SKU T38213-1 mg Category Brand:

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Products Details

Product Description

– 1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher’s disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-β-D-glucosylsphingadienine isolated from plants.

Web ID

– T38213

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H45NO7

CAS Number

– 114200-59-8

Molecular Weight

– C24H45NO7

SMILES

– CCCCCCCCCC=CCCC=CC(O)C(N)COC1OC(CO)C(O)C(O)C1O |w:14.14,10.10|

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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