0990CL
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0990CL

SKU T13983-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 341 CAD through 3,488 CAD

Products Details

Product Description

– 0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP regulation. In the cell model, low concentration of 0990CL could partially restore cAMP level, and high concentration of 0990CL (10μM) began to have negative effects on cell viability.

Web ID

– T13983

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H21N5

References

– Appleton KM,et al. Development of inhibitors of heterotrimeric Gαi subunits.Bioorg Med Chem. 2014 Jul 1;22(13):3423-3434.

CAS Number

– 511514-03-7

Molecular Weight

– C21H21N5

Compound Purity

– 0.9912

SMILES

– N(C=1N=C(C2=C(N1)C=CC=C2)C3=CC=CC=C3)C=4NC(C)(C)C=C(C)N4

Target

– Others

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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