P162-0948
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P162-0948

SKU T205592-10 mg Category Brand:

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Products Details

Product Description

– P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. It reduces cell migration and the expression of EMT-related proteins in the A549 human alveolar epithelial cell line. Furthermore, P162-0948 decreases Smad phosphorylation, indicating disruption of the TGF-β/Smad signaling pathway, making it a promising compound for pulmonary fibrosis research.

Web ID

– T205592

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H15FN4O2

CAS Number

– 1358201-44-1

Molecular Weight

– C20H15FN4O2

SMILES

– O=C(NCC1=CC=C(F)C=C1)CC2=NN=C(O2)C=3C=CC=4N=CC=CC4C3

Target

– Apoptosis

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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