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Products Details
Product Description
– Enpp-1-IN-25 (Compound 30) is an ENPP1 inhibitor with an IC50 of 8.05 nM and exhibits low oral bioavailability. By inhibiting cGAMP degradation, it effectively activates the intracellular STING pathway. Enpp-1-IN-25 can enhance immune cell infiltration and type I interferon response in the tumor microenvironment, thereby increasing the antitumor efficacy of anti-PD-L1 antibodies. It is applicable for research in cancer immunotherapy.
Web ID
– T205138
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H21N5O4S
CAS Number
– 3067908-20-4
Molecular Weight
– C15H21N5O4S
SMILES
– O=S(=O)(N)NCC1(O)CCN(C=2N=CN=C3C(OC)=CC=CC32)CC1
Target
– Others
Pathway
– Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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