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Products Details
Product Description
– VEGFR-2-IN-58 (Compound 7b) is a VEGFR-2 inhibitor with an IC50 of 42.5 nM. It shows selective cytotoxicity against cancer cells, induces cell cycle arrest at the G2/M phase, and triggers apoptosis by increasing BAX expression and decreasing Bcl2 expression. Additionally, VEGFR-2-IN-58 hampers cancer cell wound closure.
Web ID
– T204438
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H16ClN3O
Molecular Weight
– C24H16ClN3O
SMILES
– C1=CC=C(C=C1)C2=C(OC(=C2C#N)/N=C/NC3=CC=C(C=C3)Cl)C4=CC=CC=C4
Target
– Antibacterial|||Antibiotic
Pathway
– Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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