PROTAC HDAC6 degrader 3

SKU T204294-10 mg Category Brand:

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Products Details

Product Description

– PROTACHDAC6 degrader 3 (Compound 4) is a selective inhibitor and degrader of HDAC6, with an IC50 of 686 nM and a DC50 of 171 nM. It enhances the acetylation of α-tubulin. [Pink: ligand for target protein; Blue: ligand for E3ligaseVHL.]

Web ID

– T204294

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C46H56F2N10O9S

Molecular Weight

– C46H56F2N10O9S

SMILES

– CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)COCCOCCOCC(=O)NCC4=CC=CC(=C4)CNC5=NC=C(C=N5)C6=NN=C(O6)C(F)F)O

Target

– ALK

Pathway

– DNA Damage/DNA Repair|||Chromatin/Epigenetic|||PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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