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BMS-986449
Price range: 334 CAD through 4,368 CAD
Products Details
Product Description
– BMS-986449 is a CELMoD-type molecular gel that remodels the function of regulatory T cells (Treg) and enhances their anti-tumor immune responses by directing the E3 ubiquitin ligase, Cereblon, to target the degradation of IKZF2 (Helios) and IKZF4 (Eos). BMS-986449 has potential application in the study of advanced solid tumors.
Web ID
– T204091
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H21FN4O3
Molecular Weight
– C21H21FN4O3
SMILES
– CC1=C(C)C(N)=NC(C2=C(F)C([C@@H](C)N([C@H]3CCC(NC3=O)=O)C4=O)=C4C=C2)=C1
Target
– Autophagy
Pathway
– PROTAC|||Immunology/Inflammation
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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