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Products Details
Product Description
– DU-14 (PTP1B/TC-PTPPROTAC) is a potent and selective dual PROTAC degrader for PTP1B and TC-PTP, exhibiting IC50 values of 24.2 nM and 30.1 nM for the phosphatase activity of PTP1B and TC-PTP, respectively. It enhances IFN-γ signaling, promotes T cell activation, and possesses antitumor activity.
Web ID
– T203548
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C74H85BrF2N9O14PS
CAS Number
– 3053413-58-1
Molecular Weight
– C74H85BrF2N9O14PS
SMILES
– C([C@@H](NC(CC1=CC(CNC([C@@H](NC([C@H](CC2=CC=C(C(P(=O)(O)O)(F)F)C=C2)NC([C@H](CC3=CC=CC=C3)NC(CC4=CC(OC)=C(O)C=C4)=O)=O)=O)CCCCNC(=O)C5=CC(Br)=C(C)C=C5)=O)=CC=C1)=O)C(C)(C)C)(=O)N6[C@H](C(N[C@@H](C)C7=CC=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6
Target
– Phosphatase
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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