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Products Details
Product Description
– PROTAC HDAC8 Degrader-2 (compound 32a) acts as a degrader for HDAC8 with a DC50 of 8.9 nM and for HDAC6 with a DC50 of 14.3 nM. This compound is composed of a PROTAC target protein ligand HDAC8 ligand 1, an E3 ligase ligand thalidomide-4-OH, and PROTAC Linker 1,5-diaminopentane. The complex includes an E3 ubiquitin ligase ligand linked with the linker, specifically thalidomide-NH-C5-NH2.
Web ID
– T201111
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H44N10O8
Molecular Weight
– C39H44N10O8
SMILES
– O=C(NC=1C=CC(=CC1)C2=NN(C(=O)CC2C)CCCCCN)N3CC=4C=NC=CC4C3
Target
– Others
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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