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Products Details
Product Description
– PROTAC SMARCA2/4-degrader-33 (compound I-277) functions as a degrader targeting the proteins SMARCA2 and SMARCA4, exhibiting DC50s values of less than 100 nM for the degradation of SMARCA2/4 in A549 cells. After a treatment period of 24 hours, the maximum degradation rates (Dmax%) consistently exceed 90%.
Web ID
– T200608
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C44H51N11O4
CAS Number
– 2568276-36-6
Molecular Weight
– C44H51N11O4
SMILES
– NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)C5CCN(CC5)[C@H]6CC[C@H](CC6)C=7C=C8C(=CC7)N(C(=O)N8C)C9C(=O)NC(=O)CC9)C=C(N=N1)C%10=C(O)C=CC=C%10
Target
– Others
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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