Download Files:
Products Details
Product Description
– Compound I-431, also known as SMARCA2/4-degrader-2, is a PROTAC degrader targeting SMARCA2 and SMARCA4. In A549 cells, it degrades SMARCA2/4 proteins with DC50s values of less than 100 nM and achieves a maximum degradation rate (Dmax%) exceeding 90% after a 24-hour treatment.
Web ID
– T200532
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C52H64N12O6S
CAS Number
– 2568277-76-7
Molecular Weight
– C52H64N12O6S
SMILES
– NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)[C@H]5CC[C@H](C(N[C@H](C(=O)N6[C@H](C(NCC7=C(C(N(C)C)=O)C=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6)C(C)(C)C)=O)CC5)C=C(N=N1)C9=C(O)C=CC=C9
Target
– Drug Metabolite
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
1000 in stock
