PROTAC SMARCA2 degrader-17

SKU T200525-10 mg Category Brand:

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Products Details

Product Description

– PROTAC SMARCA2 degrader-17 (compound I-290) is a targeted PROTAC degrader for SMARCA2. It exhibits a DC50 of less than 100 nM and achieves a maximum degradation efficiency (Dmax%) of over 90% in A549 cells after 24 hours of treatment.

Web ID

– T200525

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C44H51N11O4

CAS Number

– 2568276-43-5

Molecular Weight

– C44H51N11O4

SMILES

– O=C1NC(=O)C(N2C(=O)N(C3=CC(=CC=C32)C4CCC(N5CCC(C6=CN=C(N=C6)N7C8CN(C=9C=C(N=NC9N)C%10=CC=CC=C%10O)CC7CC8)CC5)CC4)C)CC1

Target

– Mdm2|||p53

Pathway

– PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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