GNE-131

SKU TQ0014-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 197 CAD through 1,968 CAD

Products Details

Product Description

– GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).

Web ID

– TQ0014

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H30N4O3S

References

– Focken T, et al. Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. J Med Chem. 2018 Jun 14;61(11):4810-4831.

CAS Number

– 1629063-81-5

Molecular Weight

– C23H30N4O3S

Compound Purity

– 0.9854

SMILES

– O=S(=O)(Nc1nnc2cc(OCC34CC5CC(CC(C5)C3)C4)c(cn12)C1CC1)C1CC1

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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