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Products Details
Product Description
– ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.
Web ID
– TP2108
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H37N5O5
References
– Moss et al (2007) Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening. Anal.Biochem. 366 144 PMID:
CAS Number
– 689284-12-6
Molecular Weight
– C19H37N5O5
SMILES
– [C@@H](NC([C@@H](CC(NO)=O)CC(C)C)=O)(C(N[C@H](C(NCCN)=O)C)=O)C(C)(C)C
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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