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Tanshinone IIB
3,357 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner; TSB also suppresses the elevated Bax protein and decreased bcl-2 and caspase-3 proteins induced by staurosporine in rat cortical neurons; TSB is effective in reducing stroke-induced brain damage and may represent a novel drug candidate for further development.
Web ID
– TN2257
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H18O4
References
– Involvement of P-glycoprotein and multidrug resistance associated protein 1 in the transport of tanshinone IIB, a primary active diterpenoid quinone from the roots of Salvia miltiorrhiza, across the blood-brain barrier.Drug Metab Lett. 2007 Aug;1(3):205-17.
CAS Number
– 17397-93-2
Molecular Weight
– C19H18O4
SMILES
– Cc1coc-2c1C(=O)C(=O)c1c3CCC[C@](C)(CO)c3ccc-21
Pathway
– Proteases/Proteasome|||Neuroscience|||Apoptosis|||Membrane transporter/Ion channel
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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