AGI-43192
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AGI-43192

SKU T9729-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 110 CAD through 2,768 CAD

Products Details

Product Description

– AGI-43192 is a potent methionine adenosine transferase 2A (MAT2A) inhibitor that penetrates the blood-brain barrier. AGI-43192 inhibits S-adenosine methionine (SAM) production metabolic enzyme and methionine adenosine transferase 2A (MAT2A), which has the potential to study the role of SAM regulation in the central nervous system (CNS) and the treatment of cancer diseases.

Web ID

– T9729

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H16ClF3N6O

References

– Li M, et al. Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J Med Chem. 2022;65(6):4600-4615.

CAS Number

– 2377491-54-6

Molecular Weight

– C23H16ClF3N6O

Compound Purity

– 0.996

SMILES

– Cn1cc2cc(ccc2n1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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