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MAK-683 hydrochloride
Price range: 312 CAD through 3,088 CAD
Products Details
Product Description
– MAK683 hydrochloride embryonic ectodermal development (EED) inhibitor, also a potent PRC2 inhibitor, blocked cancer cell proliferation (IC50=1.014nM), with IC50 values of 59, 26, and 89 nM measured in EED Alphascreen, ELISA, and LC-MS assays, respectively.
Web ID
– T9681
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H18ClFN6O
References
– Dading Huang, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.
CAS Number
– 2170606-94-5
Molecular Weight
– C20H18ClFN6O
Compound Purity
– 0.9931
SMILES
– FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C(C=CC=N4)=C4C)C5=NN=CN35.Cl
Pathway
– Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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