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Products Details
Product Description
– PROTACSMARCA2 degrader-5 (Compound I-425) functions as a PROTAC degrader targeting the catalytic subunit SMARCA2 of the SWI/SNF complex. It effectively degrades SMARCA2 in MV411 and A549 cell lines with a DC50 of less than 100 nM, and also degrades SMARCA4 in MV411, exhibiting a DC50 ranging from 100-500 nM.
Web ID
– T88932
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C57H72N12O5S
CAS Number
– 2568277-68-7
Molecular Weight
– C57H72N12O5S
SMILES
– C(C12CCC(C(N[C@H](C(=O)N3[C@H](C(NCC4=CC=C(C=C4)C5=C(C)N=CS5)=O)C[C@@H](O)C3)[C@](C)(C)C)=O)(CC1)CC2)N6CCC(CC6)C=7C=NC(=NC7)N8C9CN(CC8CC9)C=%10C=C(N=NC%10N)C%11=C(O)C=CC=C%11
Product type
– PROTAC
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