PROTAC FLT-3 degrader 4
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PROTAC FLT-3 degrader 4

SKU T87986-10 mg Category Brand:

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Products Details

Product Description

– PROTACFLT-3degrader 4 is an orally active CRBN-based FLT3-PROTAC degrader that efficiently induces the degradation of FLT3-ITD via the ubiquitin-proteasome system. It demonstrates high selectivity for FLT3-ITD mutant acute myeloid leukemia (AML) cells. [Blue: CRBN ligand, Black: linker; Pink: FLT3 inhibitor].

Web ID

– T87986

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C39H41FN8O6

CAS Number

– 2956722-48-6

Molecular Weight

– C39H41FN8O6

SMILES

– O=C1N(C(=O)C=2C1=CC(=CC2)N3CCC(CN4CCN(CC(NC=5C(C)=C(/C=C6/C=7C(NC6=O)=CC=C(F)C7)NC5)=O)CC4)CC3)C8C(=O)NC(=O)CC8

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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