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Bid BH3 (80-99)
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.
Products Details
Product Description
– Bid BH3 (80-99) is a biologically active peptide and a pro-apoptotic member of the ‘BH3-only’ (BOPS) subset within the BCL-2 protein family, crucial in apoptosis regulation. It interacts with Bcl-2, Bax, and Bak to initiate their activation or inactivation, inducing cell death. Bid translocates from the cytosol to the mitochondrial membrane as part of its mechanism. Pyroglutamyl (pGlu) peptides, which can arise from Glutamine (Q) or Glutamic acid (E) at the N-terminus, have a hydrophobic γ-lactam ring that enhances stability and provides resistance to gastrointestinal proteases. These peptides are recognized variants in peptide analyses, including HPLC purity assessments.
Web ID
– T80224
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C95H161N33O32S
CAS Number
– 505070-05-3
Molecular Weight
– C95H161N33O32S
SMILES
– [C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CC(N)=O)=O)[C@H](CC)C)=O)C)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CC(O)=O)=O)CCSC)=O)CO)=O)CC(O)=O)=O)=O)[C@H](C)C)=O)CCC(N)=O)=O)C)=O)CC(C)C)=O
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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