Coibamide A

SKU T76506-5 mg Category Brand:

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Products Details

Product Description

– Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, exhibits potent antiproliferative activity, induces autophagosome accumulation via an mTOR-independent mechanism, and triggers apoptosis. Furthermore, it inhibits VEGFA/VEGFR2 expression, effectively suppressing tumor growth in glioblastoma xenografts [1] [2].

Web ID

– T76506

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C65H110N10O16

CAS Number

– 1029227-48-2

Molecular Weight

– C65H110N10O16

SMILES

– [H][C@@]1([C@@H](C)CC)N(C)C(=O)[C@H](COC)N(C)C(=O)[C@H]([C@@H](C)OC(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C)NC1=O)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](COC)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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