Talarozole
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Talarozole

SKU T7370-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 106 CAD through 781 CAD

Products Details

Product Description

– Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) that inhibits CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively, for treating acne, psoriasis, and other keratinization disorders.

Web ID

– T7370

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H23N5S

References

– Elizabeth Pavez Loriè, Chamcheu J C , Vahlquist A , et al. Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis[J]. Archives of Dermatological Research, 2009, 301(7):475-485.

CAS Number

– 201410-53-9

Molecular Weight

– C21H23N5S

Compound Purity

– 0.9751

SMILES

– CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1

Pathway

– Autophagy|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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