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CU-CPT-9a
Price range: 54 CAD through 1,075 CAD
Products Details
Product Description
– CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-
Web ID
– T7317
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H15NO2
Citations
– 1. Yang W, Sun X, Liu S, et al.TLR8 agonist Motolimod-induced inflammatory death for treatment of acute myeloid leukemia.Biomedicine & Pharmacotherapy.2023, 163: 114759.
References
– Zhang S , Hu Z , Tanji H , et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology, 2017, 14(1):58-64.
CAS Number
– 2165340-32-7
Molecular Weight
– C17H15NO2
Compound Purity
– 0.98
SMILES
– COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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