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ARQ-736
Price range: 8,720 CAD through 18,190 CAD
Products Details
Product Description
– ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may account for a significant proportion of colon cancer patients whose tumors are resistant to anti-EGFR therapy. The B-Raf protein is a key signaling molecule in the mitogen activated protein kinase (MAPK) signaling pathway and has been implicated in the pathogenesis of a variety of cancers.
Web ID
– T71184
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H25N8Na2O8PS
CAS Number
– 1228237-57-7
Molecular Weight
– C25H25N8Na2O8PS
SMILES
– [Na+].[Na+].Cn1ccc(n1)S(=O)(=O)N1CCC[C@H](C1)Nc1nccc(n1)-c1c(nc2occn12)-c1cccc(OCOP([O-])([O-])=O)c1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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