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GNE-431
Price range: 3,632 CAD through 6,400 CAD
Products Details
Product Description
– GNE-431 is a potent, selective and noncovalent Btk inhibitor with IC50 of 3.2 nM. GNE-431 showed excellent potency against the C481R, T474I, and T474M mutants. GNE-431 may provide a treatment option to patients, especially those who have acquired resistance to ibrutinib by mutation of Cys481 or Thr474.
Web ID
– T70668
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H32N10O2
CAS Number
– 1433820-83-7
Molecular Weight
– C30H32N10O2
SMILES
– O=C1C=2N(C3=C(C2)CCCC3)CCN1C4=C(CO)C(=CC=N4)C=5C=C(NC=6C=C7N(N6)CCN(C)C7)C=8N(N5)C=CN8
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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