JB062
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JB062

SKU T67952-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 312 CAD through 6,352 CAD

Products Details

Product Description

– JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It selectively exhibits cytotoxicity towards human cancer cells without affecting normal cells. The compound is applicable in research fields concerning muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.

Web ID

– T67952

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H17NO4

References

– Smith JD, et al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2023;247:115008.

CAS Number

– 2417988-00-0

Molecular Weight

– C19H17NO4

Compound Purity

– 0.9949

SMILES

– OC=1C=2C(OC(=O)C1C(=NCC3=CC=C(OC)C=C3)C)=CC=CC2

Pathway

– Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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