C004019

SKU T67834-1 mg Category PROTAC Brand: TargetMol

Price range: 421 CAD through 4,048 CAD

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Product Description

– C004019 is a small molecule PROTAC capable of targeting tau for selective protein degradation from the cell, while recruiting tau and E3 ligase (Vhl) for selective enhancement of tau ubiquitination and proteollyzation. C004019 is a candidate for AD and related tau protein diseases.

Web ID

– T67834

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C49H70N12O9S2

References

– Wang W, et al. A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models. Theranostics. 2021;11(11):5279-5295.

CAS Number

– 2417159-57-8

Molecular Weight

– C49H70N12O9S2

Compound Purity

– 0.9989

SMILES

– N(CC(NCCOCCOCCOCC(N[C@H](C(=O)N1[C@@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](O)C1)C(C)(C)C)=O)=O)(C)C4=NC(=NC(NCCC5=CC=CS5)=N4)N6CCN(C(C)=O)CCC6

Pathway

– Cytoskeletal Signaling|||PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

C004019

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