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Terbinafine
Price range: 61 CAD through 126 CAD
Products Details
Product Description
– Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.
Web ID
– T6702
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H25N
Citations
– 1. Zhao F, Huang Y, Zhang Y, et al. SQLE inhibition suppresses the development of pancreatic ductal adenocarcinoma and enhances its sensitivity to chemotherapeutic agents in vitro. Molecular Biology Reports. 2022: 1-9
2. Ye Z, Ai X, Yang K, et al.Targeting Microglial Metabolic Rewiring Synergizes with Immune Checkpoint Blockade Therapy for Glioblastoma.Cancer Discovery.2023
3. Liu Y, Wang Z, Jin H, et al.Squalene-epoxidase-catalyzed 24 (S), 25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity.Cell Reports.2024, 43(4).
References
– Vickers AE, et al. Drug Metab Dispos, 1999, 27(9), 1029-1038.
CAS Number
– 91161-71-6
Molecular Weight
– C21H25N
Compound Purity
– 0.999
SMILES
– CN(CC=CC#CC(C)(C)C)CC1=CC=CC2=C1C=CC=C2
Pathway
– Microbiology/Virology
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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