TDI-10229
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TDI-10229

SKU T64355-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 2,128 CAD

Products Details

Product Description

– TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10), displaying nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 = 195 nM). TDI-10229 exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.

Web ID

– T64355

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H16ClN5

References

– Balbach M, et al. Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization [published online ahead of print, 2021 Aug 31]. Mol Hum Reprod. 2021;gaab054.

CAS Number

– 2810887-45-5

Molecular Weight

– C16H16ClN5

Compound Purity

– 0.9777

SMILES

– Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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