Download Files:
Calcitriol
Price range: 106 CAD through 1,566 CAD
Products Details
Product Description
– Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption with parathyroid hormone.
Web ID
– T6316
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H44O3
Citations
– 1. Shang J, Zhu Z, Chen Y, et al. Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer. Theranostics. 2020, 10(13): 5845
2. Li J, Chen S, Shi J, et al.VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance.International Immunopharmacology.2024, 138: 112597.
3. Liu X, Zhang X, Ma L, et al.1, 25-Dihydroxyvitamin D3 protects against placental inflammation by suppressing NLRP3-mediated IL-1β production via Nrf2 signaling pathway in preeclampsia.Metabolism.2024: 156058.
References
– Gesmundo I, et al. Calcitriol Inhibits Viability and Proliferation in Human Malignant Pleural Mesothelioma Cells. Front Endocrinol (Lausanne). 2020 Oct 8;11:559586.
CAS Number
– 32222-06-3
Molecular Weight
– C27H44O3
Compound Purity
– 0.9994
SMILES
– C[C@@]12[C@](/C(=C/C=C/3C(=C)[C@@H](O)C[C@H](O)C3)/CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]
Pathway
– Metabolism
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
