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dCeMM2
Price range: 50 CAD through 2,272 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.
Products Details
Product Description
– dCeMM2 is a glue degrader. dCeMM2 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, leading to the ubiquitination and degradation of cyclin K.
Web ID
– T61477
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H11ClN6OS
References
– Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling [published correction appears in Nat Chem Biol. 2021 Mar;17(3):361]. Nat Chem Biol. 2020;16(11):1199-1207.
CAS Number
– 296771-07-8
Molecular Weight
– C16H11ClN6OS
Compound Purity
– 0.9968
SMILES
– Clc1ccc(NC(=O)CSc2nnc3c(n2)[nH]c2ccccc32)nc1
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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