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Products Details
Product Description
– ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
Web ID
– T6077
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H31N5O4
References
– Ditchfield C, et al. J Cell Biol. 2003, 161(2), 267-280.
CAS Number
– 331771-20-1
Molecular Weight
– C29H31N5O4
Compound Purity
– 0.9853
SMILES
– COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCOCC1
Pathway
– MAPK|||Cell Cycle/Checkpoint|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Apoptosis|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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