VB124
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VB124

SKU T60165-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 195 CAD through 3,408 CAD

Products Details

Product Description

– VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate import (IC50 value of 8.6 nM) and export (IC50 value of 19 nM) in MDA-MB-231 cells. VB124 is selective for MCT4 over MCT1 and shows minimal MCT1 inhibitory activity in MCT1-expressing BT20 cells (IC50 value of 24 μM).

Web ID

– T60165

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H23ClN2O4

References

– Cluntun AA, et.al. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. 2021 Mar 2;33(3):629-648.e10.

CAS Number

– 2230186-18-0

Molecular Weight

– C23H23ClN2O4

Compound Purity

– 0.9957

SMILES

– CC(C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1Cl)C(O)=O

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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