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Products Details
Product Description
– BI-4464, a highly selective ATP-competitive inhibitor of PTK2/FAK, exhibits an IC50 of 17 nM and serves as a PTK2 ligand for PROTAC (Proteolysis Targeting Chimera).
Web ID
– T5480
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H28F3N5O4
References
– Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.
CAS Number
– 1227948-02-8
Molecular Weight
– C28H28F3N5O4
Compound Purity
– 0.9743
SMILES
– O(C1=C2C(CCC2=O)=CC=C1)C=3C(C(F)(F)F)=CN=C(NC4=C(OC)C=C(C(NC5CCN(C)CC5)=O)C=C4)N3
Pathway
– Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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