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GNE-6640
Price range: 102 CAD through 1,808 CAD
Products Details
Product Description
– GNE-6640 is a non-covalent inhibitor targeting ubiquitin specific peptidase 7 (USP7), exhibiting IC50 values of 0.75 μM for full-length USP7, 0.43 μM for the USP7 catalytic domain, 20.3 μM for full-length USP43, and 0.23 μM for Ub-MDM2, respectively.
Web ID
– T5461
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H18N4O
References
– Kategaya L, et al. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. 2017 Oct 26;550(7677):534-538.
CAS Number
– 2009273-67-8
Molecular Weight
– C20H18N4O
Compound Purity
– 0.9864
SMILES
– CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2[nH]ncc2c1
Pathway
– Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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