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dBET6
Price range: 77 CAD through 2,208 CAD
Products Details
Product Description
– dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.
Web ID
– T5130
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C42H45ClN8O7S
Citations
– 1. Shi Y, Liao Y, Liu Q, et al.BRD4-targeting PROTAC as a unique tool to study biomolecular condensates.Cell Discovery.2023, 9(1): 1-13.
References
– Winter GE, et al. BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. Mol Cell. 2017 Jul 6;67(1):5-18.e19.
CAS Number
– 1950634-92-0
Molecular Weight
– C42H45ClN8O7S
Compound Purity
– 0.9876
SMILES
– CC=1C2=C(N3C([C@H](CC(NCCCCCCCCNC(COC4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C
Pathway
– Apoptosis|||PROTAC|||Chromatin/Epigenetic
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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