AC-264613
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AC-264613

SKU T4186-1 mg Category Brand:

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Products Details

Product Description

– AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613(AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 30 to 100 nM.

Web ID

– T4186

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H18BrN3O2

References

– Cosimi E, et al. Stereoselective Synthesis of α-Fluoro-γ-nitro Thioesters under Organocatalytic Conditions. Org Lett. 2016 Dec 2;18(23):6014-6017

CAS Number

– 1051487-82-1

Molecular Weight

– C19H18BrN3O2

SMILES

– CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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