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CBR-470-1
Price range: 56 CAD through 99 CAD
Products Details
Product Description
– CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.
Web ID
– T40063
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H20ClNO4S2
References
– Zheng J, et, al. PGK1 inhibitor CBR-470-1 protects neuronal cells from MPP+. Aging (Albany NY). 2020 Jul 10;12(13):13388-13399.
CAS Number
– 2416095-06-0
Molecular Weight
– C14H20ClNO4S2
Compound Purity
– 0.9803
SMILES
– S(=O)(=O)([C@@H]1[C@@H](NCC(C)C)CS(=O)(=O)C1)C2=CC=C(Cl)C=C2
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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