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VGSC blocker-1
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– VGSC blocker-1 is a powerful small molecule that serves as a blocker for the neonatal isoform of the VGSC subtype known as Nav1.5 (nNav1.5). It effectively blocks INa peak currents by 34.9% at a concentration of 1 μM, and demonstrates a 0.3% inhibition of cell invasion at the same concentration in the MDA-MB-231 human breast cancer cell line, without compromising cell viability.
Web ID
– T39717
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H32F2N2
References
– Dutta S, et al. Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells. Bioorg Med Chem. 2018;26(9):2428-2436.
CAS Number
– 2230472-55-4
Molecular Weight
– C24H32F2N2
SMILES
– Fc1ccc(cc1)C(CCCNCCCN1CCCCC1)c1ccc(F)cc1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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