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Products Details
Product Description
– Alizapride-13C,d3 (hydrochloride) is deuterium labeled Alizapride (hydrochloride). Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
Web ID
– HY-A0125AS
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15 13CH19D3ClN5O2
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Bleiberg H, et al. Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20.
Molecular Weight
– 355.84
SMILES
– O=C(C1=CC2=C(C=C1O[13C]([2H])([2H])[2H])NN=N2)NCC3N(CCC3)CC=C.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor;Isotope-Labeled Compounds
Isoform
– D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
