Zorifertinib

SKU T3659-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 46 CAD through 195 CAD

Products Details

Product Description

– Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectively.

Web ID

– T3659

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H23ClFN5O3

References

– Zeng Q, et al. J Med Chem. 2015, 58(20), 8200-8215.

CAS Number

– 1626387-80-1

Molecular Weight

– C22H23ClFN5O3

Compound Purity

– 0.9936

SMILES

– N(C=1C2=C(C=C(OC)C(OC(=O)N3[C@H](C)CN(C)CC3)=C2)N=CN1)C4=C(F)C(Cl)=CC=C4

Pathway

– JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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